Universidade de São Paulo (USP), São Paulo, SP, Brasil.
Our office will remain closed through Friday, September 18th as we continue to assess the damages caused by Hurricane Sally. ActiGraph team members are working remotely, however shipping delays should be expected at this time. We expect to resume regular business hours on Monday, September 21st. If you need immediate assistance, please contact us by email at email@example.com and we will respond as quickly as possible. Thank you for your continued support.
The role of moderate-to-vigorous physical activity in mediating the relationship between central adiposity and immunometabolic profile in postmenopausal women.
- Published on Aug 2017
Objectives: To analyze the role of moderate-to-vigorous physical activity (MVPA) in mediating the relationship between central adiposity and immune and metabolic profile in postmenopausal women.
Materials and Methods: Cross-sectional study comprising 49 postmenopausal women (aged 59.26 ± 8.32 years) without regular physical exercise practice. Body composition was measured by dual-energy X-ray absorptiometry. Fasting blood samples were collected for assessment of nonesterified fatty acids, tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), adiponectin, insulin and estimation of insulin resistance (HOMA-IR). Physical activity level was assessed with an accelerometer (Actigraph GTX3x) and reported as a percentage of time spent in sedentary behavior and MVPA. All analyses were performed using the software SPSS 17.0, with a significance level set at 5%.
Results: Sedentary women had a positive relationship between trunk fat and IL-6 (rho = 0.471; p = 0.020), and trunk fat and HOMA-IR (rho = 0.418; p = 0.042). Adiponectin and fat mass (%) were only positively correlated in physically active women (rho = 0.441; p = 0.027). Physically active women with normal trunk fat values presented a 14.7% lower chance of having increased HOMA-IR levels (β [95%CI] = 0.147 [0.027; 0.811]).
Conclusions: The practice of sufficient levels of MVPA was a protective factor against immunometabolic disorders in postmenopausal women.
- Diniz TA 1,2
- Rossi FE 2
- Silveira LS 2
- Neves LM 1
- Fortaleza ACS 3
- Christofaro DGD 4
- Lira FS 2
- Freitas-Junior IF 3
Grupo de Imunometabolismo e Exercício, Departamento de Educação Física, Universidade Estadual Paulista (Unesp), Presidente Prudente, SP, Brasil.
Centro de Estudos e Laboratório de Avaliação e Prescrição de Atividades Motoras (Celapam), Departamento de Educação Física, Unesp, Presidente Prudente, SP, Brasil.
Grupo de Estudos em Atividade Física e Saúde, Departamento de Educação Física, Unesp, Presidente Prudente, SP, Brasil.
Archives of Endocrinology and Metabolism