Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Viale del Tirreno 331, 56128 Calambrone, Pisa, Italy
Actigraph assessment for measuring upper limb activity in unilateral cerebral palsy
- Published on February 22, 2019
Detecting differences in upper limb use in children with unilateral cerebral palsy (UCP) is challenging and highly dependent on examiner experience. The recent introduction of technologies in the clinical environment, and in particular the use of wearable sensors, can provide quantitative measurement to overcome this issue. This study aims to evaluate ActiGraph GT3X+ as a tool for measuring asymmetry in the use of the two upper limbs (ULs) during the assessment with a standardized clinical tool, the Assisting Hand Assessment (AHA) in UCP patients aged 3–25 years compared to age-matched typically developing (TD) subjects.
Fifty children with UCP and 50 TD subjects were assessed with AHA while wearing ActiGraphs GT3X+ on both wrists. The mean activity of each hand (dominant and non-dominant, MADH and MANDH, respectively) and the asymmetry index (AI) were calculated. Two linear mixed model analyses were carried out to evaluate how dependent actigraphic variables (i.e. MANDH and AI) varied by group (TD vs UCP) and among levels of manual ability based on Manual Ability Classification System (MACS). In both models age, sex, side of hemiplegia, presence/absence of mirror movements were specified as random effects.
The MANDH was significantly lower in UCP compared to TD, while the AI was significantly higher in UCP compared to TD. Moreover, in UCP group there were significant differences related to MACS levels, both for MANDH and AI. None of the random variables (i.e. age, sex, side, presence/absence of mirror movements) showed significant interaction with MANDH and AI.
These results confirm that actigraphy could provide, in a standardized setting, a quantitative description of differences between upper limbs activity.
- Elena Beani 1,2
- Martina Maselli 3
- Elisa Sicola 1,2
- Silvia Perazza 1,2
- Francesca Cecchi 3
- Paolo Dario 3
- Irene Braito 1,2
- Roslyn Boyd 4
- Giovanni Cioni 1,2
- Giuseppina Sgandurra 1,2
Department of Clinical and Experimental Medicine, University of Pisa, Via Roma, 56125, Pisa, Italy
The BioRobotics Institute, Scuola Superiore Sant’ Anna, Viale Rinaldo Piaggio 34, 56025 Pontedera, Pisa, Italy
Queensland Cerebral Palsy and Rehabilitation Research Centre, School of Medicine, The University of Queensland, Brisbane, Australia
Journal of NeuroEngineering and Rehabilitation