Research Database

23 results for "Neuromuscular disorders"

Cumulative jerk as an outcome measure in nonambulatory Duchenne muscular dystrophy

  • Published on June 15, 2019

Objectives: Quantitative or semiquantitative outcome measures for patients with Duchenne muscular dystrophy (DMD) are important, as they can be objective indicators of the natural history of DMD; these measures also aid in the evaluation of the efficacy of various treatments. However, the most widely used standard outcome measures in patients ...


Changing physical activity behavior for people with multiple sclerosis: protocol of a randomized controlled feasibility trial (iStep-MS)

  • Published on Nov 15, 2017

Introduction: Although physical activity may reduce disease burden, fatigue and disability, and improve quality of life among people with multiple sclerosis (MS), many people with MS are physically inactive and spend significant time in sedentary behavior. Behavior change interventions may assist people with MS to increase physical activity and reduce ...


Longitudinal Growth, Diet, and Physical Activity in Young Children With Cerebral Palsy

  • Published on Sep 7, 2016

Objectives: To describe the longitudinal relationship between height-for-age z score (HZ), growth velocity z score, energy intake, habitual physical activity (HPA), and sedentary time across Gross Motor Function Classification System (GMFCS) levels I to V in preschoolers with cerebral palsy (CP). Methods: Children with CP (n = 175 [109 (62.2%) boys]; mean recruitment age 2 ...



Mobility disability and the pattern of accelerometer-derived sedentary and physical activity behaviors in people with multiple sclerosis

  • Published on Apr 1, 2016

Objective: Low physical activity and high sedentary behavior levels are major concerns in persons with multiple sclerosis (MS) and these differ depending on the level of mobility disability. However, the manner in which daily activity is accumulated is currently unknown in this population. Methods: A secondary analysis was performed on ...


Relationships among physical inactivity, deconditioning, and walking impairment in persons with multiple sclerosis

  • Published on Apr 2015

Background and Purpose: We have previously proposed a conceptual model of physical inactivity, physiological deconditioning, and walking impairment in persons with multiple sclerosis (MS) that suggests engaging in physical activity and improving physiological conditioning may lead to improvements in walking performance. This cross-sectional study examined the nature of associations among ...



Physical activity is associated with cognitive processing speed in persons with multiple sclerosis.

  • Published on May 23, 2016

Abstract: The impairment of cognitive processing speed is common, disabling, and poorly managed in multiple sclerosis (MS). This study examined the association between objectively-measured physical activity and cognitive processing speed (CPS) in a large sample of persons with MS. Patients (N=212) underwent two valid neuropsychological tests of CPS, completed the ...


Decision Trees for Detection of Activity Intensity in Youth with Cerebral Palsy

  • Published on May 2016

Purpose: To develop and test decision tree (DT) models to classify physical activity (PA) intensity from accelerometer output and Gross Motor Function Classification System (GMFCS) classification level in ambulatory youth with cerebral palsy (CP) and compare the classification accuracy of the new DT models to that achieved by previously published ...