Research Database

Does sleep disruption mediate the effects of childhood maltreatment on brain structure?

  • Published on May 31, 2018

Background: Childhood maltreatment is associated with alterations in morphology of stress susceptible brain regions. Maltreatment is also known to markedly increase risk for psychopathology and to have an enduring disruptive effect on sleep. Objective: To determine whether abnormalities in sleep continuity have effects on brain morphometry and to evaluate the ...


Classification and Processing of 24-Hour Wrist Accelerometer Data

  • Published on 2017

Background: An important step in accelerometer data analysis is the classification of continuous, 24-hour data into sleep, wake, and non-wear time. We compared classification times and physical activity metrics across different data processing and classification methods. Methods: Participants (nā€‰=ā€‰576) from the Finnish Retirement and Aging Study (FIREA) wore an accelerometer ...


Efficacy and safety of acupuncture treatment on primary insomnia: a randomized controlled trial

  • Published on Sep 2017

Objective: The objective of this study was to evaluate the efficacy and safety of acupuncture treatment for primary insomnia. Methods: We conducted a single-center, single-blinded, and randomized controlled clinical trial. Seventy-two patients with primary insomnia were randomly assigned into two groups ā€“ the acupuncture group, who received acupuncture treatment, and the ...


The relations between sleep, time of physical activity, and time outdoors among adult women

  • Published on Sep 6, 2017

Physical activity and time spent outdoors may be important non-pharmacological approaches to improve sleep quality and duration (or sleep patterns) but there is little empirical research evaluating the two simultaneously. The current study assesses the role of physical activity and time outdoors in predicting sleep health by using objective measurement ...


Sleep duration as a mediator between an alternating day and night shift work schedule and metabolic syndrome among female hospital employees.

  • Published on Feb 2018

Objectives: The main objective was to determine whether sleep duration on work shifts mediates the relationship between a current alternating day and night shift work schedule and metabolic syndrome among female hospital employees. The secondary objective was to assess whether cumulative lifetime shift work exposure was associated with metabolic syndrome. ...


Statistical modeling of circadian rhythms of physical activity

  • Published on Jun 21, 2017

Purpose: The proposed symposium will introduce novel and intuitive statistical methods for modeling the human circadian rhythm based on data collected using body-worn physical activity monitors. All methods are motivated by and applied to large observational studies. Rationale: Biological rhythms have been under intense methodological development across all disciplines of ...


Sleep pattern detection using raw tri-axial wrist and hip actigraphy in the Raine Study

  • Published on Jun 21, 2017

Sleep disorders occur in around 20% of the population and are associated with a multitude of serious health implications. Whilst polysomnography is considered the 'gold standard' in assessing sleep patterns, it is intrusive and costly hence actigraphy is increasingly being considered as a viable alternative. Current actigraphic sleep pattern detection algorithms ...




Utility of ActiGraph wear sensor in assessing wear-time in 24-hour wrist measurement

  • Published on Jun 21, 2017

There are no standard procedures for identifying wake wear, sleep wear and non-wear time from the 24-h accelerometer recordings. Participant diaries increase participant burden and frequently have missing values. The Choi algorithm identifies 90-min consecutive zero counts as non-wear time, allowing for 2 minutes of non-zero counts, thus possibly ignoring short ...